Copper-catalysed α-selective allylic alkylation of heteroaryllithium reagents.
نویسندگان
چکیده
2-Allyl-substituted thiophenes and furans are synthesised efficiently in a direct procedure using 2-heteroaryllithium reagents and allyl bromides and chlorides catalysed by ligand-free copper(i). The reactions take place under mild conditions, with excellent α-selectivity, high functional group tolerance and good yields for the SN2 products.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 46 شماره
صفحات -
تاریخ انتشار 2014